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1

Delivery of nanomedicines to extracellular and intracellular compartments of a solid tumor

Yinghuan Li, Jie Wang, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Advanced Drug Delivery Reviews

Year:

2012

Language:

english

File:

PDF, 921 KB

english, 2012

2

Target Site Delivery and Residence of Nanomedicines: Application of Quantitative Systems Pharmacology

Au, Jessie L.-S., Abbiati, Roberto A., Wientjes, M. Guillaume, Lu, Ze, Ishikawa, Yoshihiro

Journal:

Pharmacological Reviews

Year:

2019

Language:

english

File:

PDF, 1.45 MB

english, 2019

3

High-performance liquid chromatographic analysis of 2',3'-dideoxyinosine in biological samples

M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1991

Language:

english

File:

PDF, 426 KB

english, 1991

4

Evaluation of a modified high-performance liquid chromatography assay for acebutolol and its major metabolite

Theodor W. Guentert, Guillaume M. Wientjes, Robert A. Upton, Daniel L. Combs, Sidney Riegelman

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1979

Language:

english

File:

PDF, 703 KB

english, 1979

5

Isocratic high-performance liquid chromatographic determination of thiacetazone by direct injection of plasma into an internal surface reversed-phase column

Di Song, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 393 KB

english, 1997

6

Pharmacokinetics of 2′,3′-dideoxyadenosine in dogs

M. Guillaume Wientjes, Michael E. Placke, Ming J -W. Chang, John G. Page, William M. Kluwe, Joseph E. Tomaszewski

Journal:

Investigational New Drugs

Year:

1991

Language:

english

File:

PDF, 711 KB

english, 1991

7

Effect of uridine coadministration on 5′-deoxy-5-fluorouridine disposition in rats

J. Lai-Sim Au, M. Guillaume Wientjes, Steven L. Bramer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 629 KB

english, 1988

8

Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer

Elaine T. Lam, Jessie L.- S. Au, Gregory A. Otterson, M. Guillaume Wientjes, Ling Chen, Tong Shen, Yong Wei, Xiaobai Li, Tanios Bekaii-Saab, Anthony J. Murgo, Rhonda R. Jensen, Michael Grever, Miguel

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 422 KB

english, 2010

9

A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect

Nancy J. Millenbaugh, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

10

Bladder tissue pharmacokinetics of intravesical taxol

Di Song, M. Guillaume Wientjes, J. L.-S. Au

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 194 KB

english, 1997

11

Pharmacologic effects of paclitaxel in human bladder tumors

Jessie L.-S. Au, John Kalns, Yuebo Gan, M. Guillaume Wientjes

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 344 KB

english, 1997

12

Cremophor reduces paclitaxel penetration into bladder wall during intravesical treatment

Ian Knemeyer, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 172 KB

english, 1999

13

Regional heterogeneity and pharmacodynamics in human solid tumor histoculture

Jean R. Weaver, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 145 KB

english, 1999

14

Formulating Paclitaxel in Nanoparticles Alters Its Disposition

Teng Kuang Yeh, Ze Lu, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 364 KB

english, 2005

15

Expression of Basic Fibroblast Growth Factor Correlates with Resistance to Paclitaxel in Human Patient Tumors

Yuebo Gan, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 353 KB

english, 2006

16

Nontoxic Suramin as a Chemosensitizer in Patients: Dosing Nomogram Development

Danny Chen, Sae Heum Song, M. Guillaume Wientjes, Teng Kuang Yeh, Liang Zhao, Miguel Villalona-Calero, Gregory A. Otterson, Rhonda Jensen, Michael Grever, Anthony J. Murgo, Jessie L-S. Au

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 558 KB

english, 2006

17

Effects of Carrier on Disposition and Antitumor Activity of Intraperitoneal Paclitaxel

Max Tsai, Ze Lu, Jie Wang, Teng-Kuang Yeh, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 564 KB

english, 2007

18

Intravesical Treatments of Bladder Cancer: Review

Zancong Shen, Tong Shen, M. Guillaume Wientjes, Michael A. O’Donnell, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2008

Language:

english

File:

PDF, 214 KB

english, 2008

19

Determinants of Paclitaxel Uptake, Accumulation and Retention in Solid Tumors

Seong H. Jang, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Investigational New Drugs

Year:

2001

Language:

english

File:

PDF, 150 KB

english, 2001

20

A Quantitative Assay of Telomerase Activity

Yuebo Gan, Jie Lu, Andy Johnson, M. Guillaume Wientjes, David E. Schuller, Jessie L-S Au

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 564 KB

english, 2001

21

Accuracy and Precision of Pharmacodynamic Exponent

Nancy J. Millenbaugh, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 770 KB

1999

22

Antiproliferative and Cytotoxic Effects of Geldanamycin, Cytochalasin E, Suramin and Thiacetazone in Human Prostate Xenograft Tumor Histocultures

Yuebo Gan, Jessie L.-S. Au, Jie Lu, M. Guillaume Wientjes

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 3.50 MB

1998

23

Physiologically Based Pharmacokinetic Models of 2′,3′-Dideoxyinosine

Hyo-Jeong K. Kang, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 652 KB

1997

24

A Method to Study Drug Concentration–Depth Profiles in Tissues: Mitomycin C in Dog Bladder Wall

M. Guillaume Wientjes, James T. Dalton, Robert A. Badalament, Bharat M. Dasani, Joseph R. Drago, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 1.33 MB

1991

25

Nonlinear Disposition of Intravenous 2′,3′-Dideoxyinosine in Rats

M. Guillaume Wientjes, Elora Mukherji, Jessie L-S. Au

Journal:

Pharmaceutical Research

Year:

1992

File:

PDF, 1.10 MB

1992

26

Pharmacokinetics of Oral 2′,3′-Dideoxyinosine in Rats

M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1992

File:

PDF, 783 KB

1992

27

Pharmacokinetic Interaction Between Intravenous 2′,3′-Dideoxyinosine and Pentamidine in Rats

Teng-Kuang Yeh, Hyo-Jeong K. Kang, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 881 KB

1996

28

Differential Effect of Taxol in Rat Primary and Metastatic Prostate Tumors: Site-Dependent Pharmacodynamics

Wan-Ching Yen, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 5.24 MB

1996

29

Use of Drug Kinetics in Dermis to Predictin VivoBlood Concentration After Topical Application

Xiang Gao, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1008 KB

1995

30

Extensive Absorption of 2′,3′-Dideoxyinosine by Intratracheal Administration in Rats

Xiang Gao, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.05 MB

1995

31

Penetration Kinetics of 2′,3′-Dideoxyinosine in Dermis Is Described by the Distributed Model

Elora Gupta, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 858 KB

1995

32

Absorption of 2′, 3′-Dideoxyinosine from Lower Gastrointestinal Tract in Rats and Kinetic Evidence of Different Absorption Rates in Colon and Rectum

Steven L. Bramer, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1.42 MB

1993

33

Histocultures of Patient Head and Neck Tumors for Pharmacodynamics Studies

Jessie L.-S. Ail, M. Guillaume Wientjes, Thomas J. Rosol, Antoinette Koolemans-Beynen, Eric A. Goebel, David E. Schuller

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1.64 MB

1993

34

Enhanced Drug-Induced Apoptosis Associated with P-Glycoprotein Overexpression Is Specific to Antimicrotubule Agents

Dong Li, Seong H. Jang, Jonghan Kim, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

35

Suramin as a Chemosensitizer: Oral Pharmacokinetics in Rats

Adam Ogden, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 120 KB

english, 2004

36

Improving delivery and efficacy of nanomedicines in solid tumors: role of tumor priming

Wang, Jie, Lu, Ze, Gao, Yue, Wientjes, M Guillaume, Au, Jessie L-S

Journal:

Year:

2011

Language:

english

File:

PDF, 6.64 MB

english, 2011

37

Pancreatic Cancer: Pathobiology, Treatment Options, and Drug Delivery

Jing Li, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

The AAPS Journal

Year:

2010

Language:

english

File:

PDF, 181 KB

english, 2010

38

Bladder Tissue Pharmacokinetics of Intravesical Mitomycin C and Suramin in Dogs

Leijun Hu, M. Guillaume Wientjes, Jing Li, Jessie L.-S. Au

Journal:

The AAPS Journal

Year:

2010

Language:

english

File:

PDF, 149 KB

english, 2010

39

Delivery of siRNA Therapeutics: Barriers and Carriers

Jie Wang, Ze Lu, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

The AAPS Journal

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

40

Relationships between Liposome Properties, Cell Membrane Binding, Intracellular Processing, and Intracellular Bioavailability

Yinghuan Li, Jie Wang, Yue Gao, Jiabi Zhu, M. Guillaume Wientjes, Jessie L.-S. Au

Journal:

The AAPS Journal

Year:

2011

Language:

english

File:

PDF, 866 KB

english, 2011

41

Effects of bladder resorption on pharmacokinetic data analysis

James T. Dalton, M. Guillaume Wientjes, Jessie L-S. Au

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1994

Language:

english

File:

PDF, 1006 KB

english, 1994

42

Tissue pharmacokinetics of 2′,3′-dideoxyinosine in rats

Hyo-Jeong Kuh Kang, M.Guillaume Wientjes, Jessie L.-S. Au

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 711 KB

english, 1994

43

Telomere maintenance in telomerase-positive human ovarian SKOV-3 cells cannot be retarded by complete inhibition of telomerase

Yuebo Gan, Yiqun Mo, Jeffrey Johnston, Jie Lu, M.Guillaume Wientjes, Jessie L.-S Au

Journal:

Year:

2002

Language:

english

File:

PDF, 271 KB

english, 2002

44

Differential time dependency of antiproliferative and apoptotic effects of taxol in human prostate tumors

Chiung-Tong Chen, Jessie L.-S. Au, Yuebo Gan, M. Guillaume Wientjes

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

1997

Language:

english

File:

PDF, 810 KB

english, 1997

45

Phase I Evaluation of Low-Dose Suramin as Chemosensitizer of Doxorubicin in Dogs with Naturally Occurring Cancers

Carrie E. Kosarek, Xiao Hu, C. Guillermo Couto, William C. Kisseberth, Eric M. Green, Jessie L. S. Au, M. Guillaume Wientjes

Journal:

Journal of Veterinary Internal Medicine

Year:

2006

Language:

english

File:

PDF, 140 KB

english, 2006

46

Use of pharmacologic data and computer simulations to design an efficacy trial of intravesical mitomycin C therapy for superficial bladder cancer

M. Guillaume Wientjes, Robert A. Badalament, Jessie L -S. Au

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 1016 KB

english, 1993

47

Biodegradable intraprostatic doxorubicin implants

Ronnie Ortiz, Jessie L-S. Au, Ze Lu, Yuebo Gan, M. Guillaume Wientjes

Journal:

The AAPS Journal

Year:

2007

Language:

english

File:

PDF, 1.15 MB

english, 2007

48

Quantitative image analysis of intra-tumoral bFGF level as a molecular marker of paclitaxel resistance

Colin T Walsh, Yong Wei, M Guillaume Wientjes, Jessie LS Au

Journal:

Journal of Translational Medicine

Year:

2008

Language:

english

File:

PDF, 603 KB

english, 2008

49

Phase I/II Trial of 5-Fluorouracil and a Noncytotoxic Dose Level of Suramin in Patients with Metastatic Renal Cell Carcinoma

Saby George, Robert Dreicer, Jessie J.L. Au, Tong Shen, Brian I. Rini, Susan Roman, Matthew M. Cooney, Tarek Mekhail, Paul Elson, Guillaume M. Wientjes, Ram Ganapathi, Ronald M. Bukowski

Journal:

Clinical Genitourinary Cancer

Year:

2008

Language:

english

File:

PDF, 134 KB

english, 2008

50

Predictive Models of Diffusive Nanoparticle Transport in 3-Dimensional Tumor Cell Spheroids

Gao, Yue, Li, Mingguang, Chen, Bin, Shen, Zancong, Guo, Peng, Wientjes, M. Guillaume, Au, Jessie L.-S.

Journal:

The AAPS Journal

Year:

2013

Language:

english

File:

PDF, 587 KB

english, 2013